Materials and methods for cell-free expression of vaccine epitope concatemers patent

Materials and methods for cell-free expression of vaccine epitope concatemers

The present disclosure provides materials and methods for cell-free expression of epitopes for immunotherapy applications. In particular, the present disclosure provides materials and methods for expressing concatenated epitopes using a cell-free protein synthesis platform for high throughput, large scale, and unbiased epitope screening and the generation of multi-epitope vaccines.

Publication details

Recorded assignee: Leidos, Inc
Publication number: US 11608363 B2
Publication type: Utility patent grant
Publication date: Mar 21, 2023
Filing date: Jul 1, 2019
CPC classes: A61K39/085, C07K14/31, A61K39/116, C07K14/195, G01N33/56938, G01N33/6878, A61K39/00, A61K2039/521, A61K2039/522, A61K2039/575, A61K2039/645, A61K2039/70, C07K2319/00, G01N2333/31
Inventors: Chappell; Stephen A., Mauro; Vincent P., Dresios; John

Party names reflect the published document. Current ownership and legal status can change.

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